The distinguished team of cardiovascular scientists of the Greenberg Division of Cardiology are at the forefront of cardiovascular imaging, electrophysiology, and computational modeling. This work complements our long history of establishing new diagnostic and therapeutic modalities for our patients with coronary artery disease, arrhythmias, diabetes, and heart failure. Our investigators focus on integrating our newfound scientific knowledge with advances in cardiovascular diagnostic and imaging modalities to create new ways to practice cardiology.
- How can we devise and deploy new interventional strategies to treat arrhythmias, advanced valvular diseases, and obstructive disease in the coronary and peripheral vasculature?
- How do we integrate clinical information with advanced high resolution imaging of the heart to predict how cardiac patients will recuperate, and identify those who need more intensive therapy?
- Can we identify patients with coronary artery disease in whom mitral regurgitation will be reduced or eliminated by coronary revascularization?
- What genetic and clinical markers identify individuals as those who are at significant risk of pulmonary hypertension and its complications?
- How can the integration of clinical phenotyping, advanced imaging, exercise physiology and advanced phenotyping best characterize pulmonary vascular disease and cardiac adaptation?
- What readily available markers (from electrocardiogram or echocardiogram) can predict the progression of diabetic heart disease, or its improvement with risk factor and diabetes control?
- How can we integrate advanced imaging information with genetic background and biomarkers to predict and prevent aortic dissection for patients with genetically-mediated aortic aneurysms?
- What is the role of left atrial cardiomyopathy in causation of heart failure, pulmonary hypertension and stroke?
- What are the genetic and cellular mechanisms of various types of arrhythmias?
- How will computational strategies provide accurate models to predict the complex interactions of proteins and cells as they evolve during heart disease? How can they be used to illuminate mechanisms of cardiac arrhythmias and help to design treatments for them?
- How can we re-program stem cells to test how mutations in cardiac cells cause unexplained sudden death in young people?