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Department of Medicine



The division conducts promising state-of-the-art research to generate new knowledge and improve understanding with the ultimate goal of applying the latest scientific and medical advances for the prevention, detection, and treatment of patients with endocrine diseases.

Drs. Anthony Hollenberg, M.D., Marcus Goncalves, M.D., Ph.D., M.S.E., and Kristen Vella, Ph.D. began their research in the new Belfer Building in 2018. The focus of Dr. Anthony Hollenberg’s laboratory is the molecular action of thyroid hormones. Dr. Hollenberg was among the first to identify that thyrotropin-releasing hormone (TRH) neurons in the hypothalamus serve as integrators of metabolic input, setting thyroid hormone levels within the context of body weight. He was also among the first to identify the role of specific co-repressors in negative regulation by the thyroid, helping to establish the idea that hormone sensitivity is due to the quantity of co-repressors present. Dr. Hollenberg has had an independent research laboratory since 1993 and with continuous funding from the NIH since 1995. Recently, the Hollenberg Laboratory has begun a new program investigating the development of functioning thyroid follicular cells from embryonic stem cells.

In 2019, Dr. Laura Alonso, M.D. was recruited to the Division of Endocrinology, Diabetes, and Metabolism to serve as Division Chief and as Director of the Joan and Sanford I. Weill Center for Metabolic Health. Dr. Alonso is a leading investigator in pancreatic beta cell regeneration. The beta cells in the pancreas make insulin to help the body process sugar, but in type 1 diabetes, patients’ beta cells have been destroyed by the immune system, and in type 2 diabetes, patients have too few beta cells to meet the increased insulin needs of the body. Dr. Alonso’s research focuses on understanding how the pancreas in healthy people is able to produce enough beta cells to meet their need for insulin, with the goal of leveraging these discoveries to improve patient care. Even with the best therapies currently available, many patients with diabetes are not able to achieve adequate blood sugar control, and existing therapies (e.g., insulin injections) are expensive and do not address the root cause of the disease: shortage of beta cells.

Current grants

Clinical and Translational Science Center (CTSC) Weill Cornell Medical College’s $49 million NIH-funded Clinical and Translational Science Award (CTSA).
PI: Dr. Julianne Imperato-McGinley 

NCI K08 CA230318. The Role of Hypoketonemia in the Cancer Anorexia-Cachexia Syndrome.
PI: Dr. Marcus Goncalves

NIDDK R01 DK105029. Thyroid Follicular Cell Development in Mice and Humans.
PI: Dr. Anthony Hollenberg

NIDDK R01 DK117940. Thyroid Hormone Signaling in Human Hepatocytes.
PI: Dr. Anthony Hollenberg

NIDDK R01 DK056123. Corepressor Regulation of Nuclear Receptor Action.
PI: Dr. Anthony Hollenberg

NIDDK, The Epidemiology of Diabetes Intervention and Complications Trial (EDIC), a continuation of the multicenter Diabetes Control and Complications Trial (DCCT) evaluating the effect of intensive glucose control on both microvascular and macrovascular complications of diabetes.
Site PI: Dr. Naina Sinha

The Louis and Rachel Rudin Foundation, Inc. Research on Reversing Pre-Diabetes by Utilizing a Change in Food Order.
PI: Alpana Shukla

NIDDK R01 DK113300. Role of GRP78 in beta cell adaptation in obesity and diabetes.
PI: Dr. Laura C. Alonso

NIDDK R01 DK114686. ATF6 and the Beta Cell.
PI: Dr. Laura C. Alonso

NIDDK R01 DK124906. Role of Polyamines and Hypusine in Nutrient-Induced Beta-Cell Growth and Replication.
PI: Dr. Laura C. Alonso

NIDDK R01 DK050581. Transcriptional and Translational Mechanisms Governing Beta Cell Function.
PI: Dr. Laura C. Alonso

NIDDK R01 DK117137. Regulation and Function of the Type 2 Diabetes-Associated C2CD4A/B Locus.
PI: Dr. Laura C. Alonso

ADA 1-18-IBS-233. T2D risk-SNPs at the CDKN2AB locus.
PI: Dr. Laura C. Alonso

WCMC Department of Medicine Fund for the Future Program.
PI: Dr. Megan Ritter

ATA The Role of Nuclear Corepressor 1 in Thyroid Hormone Signaling.
PI: Dr. Megan Ritter

United Health Group SS 202201-01. Weill Cornell Medicine United Health Group Clinical Scholars Program in Obesity Medicine.
PI: Dr. Louis Aronne

AACR 20-40-12-DANT. Metabolic regulation of lung cancer cachexia by STAT-3.
PI: Dr. Ezequiel Dantas

Pfizer PI 200605-01. Pfizer Collaborative Research Agreement.
PI: Dr. Marcus Goncalves


Lung Cancer Research Foundation. Molecular Mechanisms of Cachexia in Non-Small Cell Lung Cancer.
PI: Dr. Marcus Goncalves

Contact Information

Endocrinology, Diabetes & Metabolism

Laura Alonso, M.D., Chief

Andrew Crawford, Administrator
413 E 69th Street, Rm BB-618
Tel: (646) 962-5629

Ashley Baptiste, Administrative Assistant
413 East 69th Street
Tel: (646) 962-6193

Patient Appointments & Inquiries

1305 York Avenue, Floor 4
New York, NY 10021
Tel: (646) 962-8690
Fax: (646) 962-0114

156 William Street, 6th Floor
New York, NY 10038
Tel: (646) 962-5665
Fax: (646) 962-5687

Comprehensive Weight Control Center
1165 York Avenue
New York, NY 10065
Tel: (646) 962-2111
Fax: (646) 962-0159

Division Events

Division News

Division Publications

Clinical Trials

Patient Care Links

Division of Endocrinology
Comprehensive Weight Control Center
PDF icon  Sick Day Management for Adults with Type 1 Diabetes
PDF icon  Manejo de un Día de Enfermedad para Adultos con Diabetes Tipo 1
PDF icon  DKA Diabetic Ketoacidosis
PDF icon  CAD Cetoacidosis diabética