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Musculoskeletal Infections

The care of patients with diverse musculoskeletal infections has constituted a critical part of the subspecialty of Infectious Diseases since the development of antibiotics, and remains so today. As populations of the aged and immunocompromised expand, as the microbiological and surgical complexities of patients increase, and as the indications for and popularity of orthopedic interventions continue to grow, the role of infectious disease-trained physicians in the prevention, diagnosis and therapy of these infections has grown. Hospital for Special Surgery (HSS), across the street from New York Presbyterian Hospital / Weill Cornell campus, specializes in the Orthopedic and Rheumatologic needs of patients. HSS is nationally ranked as #1 for Orthopedics and # 3 in Rheumatology (US News & World Report; 2019-2020) and has the highest volume of orthopedic surgery in the United States. Infectious diseases at HSS are likely to involve patients with infections of prosthetic joints or other orthopedic grafts and hardware, and patients with infectious complications of a variety of rheumatologic diseases. They may be immunosuppressed by their underlying collagen vascular disease or by their immunomodulatory therapy. The Infectious Diseases Fellowship rotation includes a substantial clinical exposure to our patient population, and the clinical problem-solving process we have developed to analyze, diagnose, and treat these patients.

Henry MW, Brause BD, Miller AO. Infection and Perioperative Orthopedic Care. In: Perioperative Care of the Orthopedic Patient, 2nd Edition; Eds. CR MacKenzie, CN Cornell, SG Memtsoudis. Springer, New York, Chapter 27, pp 327-341, 2020.

Carli AV, Miller AO, Kapadia M, Chiu YF, Westrich GH, Brause BD, Henry MW. Assessing the Role of Daptomycin as Antibiotic Therapy for Staphylococcal Prosthetic Joint Infection. J Bone Jt Infect. 2020 Mar 30;5(2):82-88.

Boyle KK, Kapadia M, Landy DC, Henry MW, Miller AO, Westrich GH. Utilization of Debridement, Antibiotics, and Implant Retention for Infection After Total Joint Arthroplasty Over a Decade in the United States. J Arthroplasty. 2020 Mar 21:S0883-5403(20)30277-1.

Lam A, Richardson SS, Buksbaum J, Markowitz J, Henry MW, Miller AO, Rozbruch SR, Fragomen AT. Chronic Osteomyelitis of the tibia and ankle treated with Limb Salvage Reconstruction. J Bone Jt Infect. 2019 Dec 10;4(6):306-313.

Schwarz EM, McLaren AC, Sculco TP, Brause B, Bostrom M, Kates SL, Parvizi J, Alt V, Arnold WV, Carli A, Chen AF, Choe H, Coraça-Huber DC, Cross M, Ghert M, Hickok N, Jennings JA, Joshi M, Metsemakers WJ, Ninomiya M, Nishitani K, Oh I, Padgett D, Ricciardi B, Saeed K, Sendi P, Springer B, Stoodley P, Wenke JC; Hospital for Special Surgery 2019 Biofilm Symposium Workgroup. Adjuvant antibiotic-loaded bone cement: Concerns with current use and research to make it work. J Orthop Res. 2020 Jan 30:10.1002/jor.24616.