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Basic and Translational Research

With over $8 million in research funding in 2017 alone, our division is actively engaged in exciting NIH sponsored research in COPD, pulmonary fibrosis, pneumonia, pulmonary infections in the aged population, pulmonary hypertension, acute respiratory distress syndrome, sepsis, biomarker discovery, among many other diseases. Fellows who choose to pursue basic science research or laboratory based studies of human samples have many resources at their disposal. From world class mentors, to access to already existing human and mouse samples, to the CTSC core laboratories which can supplement fellow’s work in the lab, to statistical support within the division for interpreting proteomic, metabolomics, and other large data sets, fellows have all the resources needed to complete their projects and compete for competitive funding. A divisional T32 is available to provide a flexible, robust, multidisciplinary approach to mentored research training including the support for additional year(s) of protected research training.

Examples of basic and translational investigators associated with the division and their work

A Choi (Stress response genes and antioxidant enzymes in a variety of models of lung disease and acute respiratory distress syndrome)

Stout-Delgado (Role of the inflammasome in an aged pneumonia model)

Cloonan (Dysregulated iron and mitochondrial metabolism in chronic lung disease)

Shaykhiev (Smoking related reprogramming of the small airway epithelium)

Cho (Dysregulated glucose metabolism in exacerbations of idiopathic pulmonary fibrosis)

Crystal (Biology of the airway epithelium and the lower respiratory tract in COPD)

Silver (Mast cells and their pathophysiological contribution to inflammation in lung disease)

Plataki (Obesity and ventilator induced lung injury)

Monticelli (Innate immune regulation of airway inflammation)

Artis (Pathways that regulate innate and adaptive immune cell function at barrier surfaces)

Rafii (Stem cell biology and angiogenesis related to lung tissue regenerative medicine)

Worgall (Pulmonary infections and lung immune responses relevant to pediatric lung diseases including asthma and cystic fibrosis)

Hajjar (Intersection of hemostasis and angiogenesis)

Ding (Vascular regulation of lung regeneration and repair)

M Choi (Molecular mechanism(s) of tissue inflammation and fibrosis in the pathogenesis of chronic diseases)

Nathan (How macrophages protect the host from intracellular microbial pathogens)

Cantley (Biochemical basis for metabolic control of cell growth)

Rhee (Systems-level metabolic studies of the human pathogen M. tuberculosis)

Cohen (Lipid metabolism in tissue injury)

Coller (Molecular interactions related to platelet physiology, thrombosis, vascular biology, and adhesion phenomena)

Lyden (Tumor exosomes in metastasis related to pediatric cancers)

Pamer (Infections associated with cancer therapy focusing on intestinal and respiratory microbiota)

Lipkin (Computational biology, and genomics to understand the contribution and mechanisms of constitutional risk variants in disease)

Golightly (Molecular parasitology)

Pulmonary and Critical Care Medicine

Fernando J. Martinez, M.D., M.S., Chief

Pulmonary and Critical Care Medicine Fellowship

Meredith Turetz, M.D., Program Director
Robert Kaner, M.D., Associate Program Director
Bradley Hayward, M.D., Associate Program Director

Patrycja Golinska, M.S., Program Coordinator
Tel: (646) 962-2738
Fax: (646) 962-0286