Initiated in 2002, the award is given to fellows within the Weill Department of Medicine who have performed outstanding research. This year's finalists were presented at Medicine Grand Rounds on June 23.
The exciting new algorithm, MethSig, analyzes the thousands of DNA methylation changes detected in tumor cells and infers which ones are likely driving tumor growth.
IPF develops when the lungs become damaged or scarred, making it difficult to breathe. Researchers have long been searching for a better mechanistic understanding of IPF that could lead to better treatment.
Four faculty in the WDOM have received the ASCI Council Young Physician-Scientist Award. This prestigious award recognizes physician-scientists who are early in their first faculty appointment and have made notable achievements in their research.
In a collaborative study, investigators have implemented advanced technology and analytics to map, at single-cell resolution, the cellular landscape of diseased lung tissue in severe COVID-19 and other infectious lung diseases.
Investigators found that patients with Crohn’s disease have an overabundance of an inflammation-producing gut bacteria. A metabolite produced by this bacteria interacts with the immune system cells in the lining of the intestine.
Dr. Leandro Cerchietti and colleagues have published a paper in Cancer Discovery that has revealed a critical connection between lymphoma tumors and their microenvironments, which consist of different ecosystems of cells and treatment responsiveness.
Dr. Ari Melnick and team have published a breakthrough finding in Nature Immunology that has identified Smc3 as a critical gene in the development of the body’s immune response (B cells).
Results from an international Phase 3 clinical trial have led to the U.S. Food and Drug Administration’s approval of oral azacytidine (Onureg) as a maintenance therapy for AML, which is now being used as part of standard patient care.
The researchers analyzed data from the REGARDS Study, which tracked cardiovascular-related outcomes in over 20,000 people for a decade, to identify adverse social determinants of health that can lead to a higher likelihood of a fatal heart attack.