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Research

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Dr. Martinez Publishes Key Findings in JAMA on Treating Idiopathic Pulmonary Fibrosis Using a Novel Trial Design

Dr. Fernando Martinez
IPF develops when the lungs become damaged or scarred, making it difficult to breathe. Researchers have long been searching for a better mechanistic understanding of IPF that could lead to better treatment.

Four WDOM Faculty Receive the 2021 ASCI Council Young Physician-Scientist Award

Four faculty in the WDOM have received the ASCI Council Young Physician-Scientist Award. This prestigious award recognizes physician-scientists who are early in their first faculty appointment and have made notable achievements in their research.

Dr. Schwartz Co-Senior Author on Pivotal Publication in Nature: Lung Pathology in COVID-19

Dr. Robert E. Schwartz
In a collaborative study, investigators have implemented advanced technology and analytics to map, at single-cell resolution, the cellular landscape of diseased lung tissue in severe COVID-19 and other infectious lung diseases.

Dr. Longman and Colleagues Publish Critical Findings on a Type of Gut Bacteria and Crohn’s Disease

Dr. Randy Longman
Investigators found that patients with Crohn’s disease have an overabundance of an inflammation-producing gut bacteria. A metabolite produced by this bacteria interacts with the immune system cells in the lining of the intestine.

Dr. Cerchietti and Colleagues Publish Novel Advance on Lymphoma Tumors and their Microenvironments in Cancer Discovery

Dr. Leandro Cerchietti
Dr. Leandro Cerchietti and colleagues have published a paper in Cancer Discovery that has revealed a critical connection between lymphoma tumors and their microenvironments, which consist of different ecosystems of cells and treatment responsiveness.

Dr. Melnick and Team Identify a Gene Critical in B Cell Immune Response

Illustration of normal (left) or reduced (right) levels of Smc3
Dr. Ari Melnick and team have published a breakthrough finding in Nature Immunology that has identified Smc3 as a critical gene in the development of the body’s immune response (B cells).

Dr. Roboz Publishes Key Finding in NEJM on Oral Azacitidine as Maintenance Therapy for AML

Dr. Gail Roboz
Results from an international Phase 3 clinical trial have led to the U.S. Food and Drug Administration’s approval of oral azacytidine (Onureg) as a maintenance therapy for AML, which is now being used as part of standard patient care.

Dr. Safford and Colleagues Publish Pivotal Paper in Circulation: Social Determinants to Prevent Fatal Heart Attacks

Dr. Monika Safford
The researchers analyzed data from the REGARDS Study, which tracked cardiovascular-related outcomes in over 20,000 people for a decade, to identify adverse social determinants of health that can lead to a higher likelihood of a fatal heart attack.

Findings on a Key Genetic Driver of Lymphomas Published in Nature

Dr. Ari Melnick
Dr. Ari Melnick and colleagues have published breakthrough findings that show certain histone H1 mutations are drivers of lymphoma.

Dr. Iliev Receives Pathogenesis of Infectious Disease Award from Burroughs Wellcome Fund

Dr. Iliyan Iliev
The award provides early-career scientists with $500,000 over five years to investigate the interplay between humans and pathogens, and how such encounters can lead to disease.

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