A team of intercampus investigators has received a $3.65 million grant from the NIH to develop an inexpensive method for accurately diagnosing UTIs in kidney transplant patients by carrying out molecular profiling of cell-free DNA in urine.
In this paper, which reflected further analysis stemming from their previous paper published in Nature Communications (December 2019), 168 kidney transplant recipients, who provided 510 fecal specimens, were evaluated.
The CHAP project is a large multicenter pragmatic randomized trial that is comparing two different strategies for managing hypertension during pregnancy in women who had elevated blood pressure prior to pregnancy.
Until now, vital data had been lacking on graft and patient outcomes in kidney transplant recipients and the management of their immunosuppression in the setting of Covid-19.
This award is presented annually to members of the Weill Department of Medicine below the rank of professor who perform on outstanding levels in the areas of clinical and/or basic biomedical research.
Initiated in 2002, the award is given to fellows within the Weill Department of Medicine who have performed outstanding research. This year's finalists were presented at Medicine Grand Rounds on June 17.
In a collaborative study, Dr. John R. Lee and colleagues revealed a first-of-its-kind discovery showing that the abundance of uropathogens in the gut is associated with future development of UTI.
Dr. Suthanthiran's talk was entitled “Monitoring the Allograft in the 21st Century: From the Microscope to Molecular Scan.”
The paper illuminates a technique that has enabled a low-cost urine test that can identify thousands of bacteria and viruses in humans. Importantly, infections causing tissue damage can be readily discerned.
The newsletter’s feature was in recognition of Dr. Lee’s pivotal abstract that presented an evaluation of the gut microbiota in 169 kidney transplant recipients.